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Autosomal dominant nocturnal frontal lobe epilepsy
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Autosomal dominant nocturnal frontal lobe epilepsy : ウィキペディア英語版
Autosomal dominant nocturnal frontal lobe epilepsy

Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is an epileptic disorder that causes frequent violent seizures during sleep. These seizures often involve complex motor movements, such as hand clenching, arm raising/lowering, and knee bending. Vocalizations such as shouting, moaning, or crying are also common. ADNFLE is often misdiagnosed as nightmares. Attacks often occur in clusters and typically first manifest in childhood. There are four known loci for ADNFLE, three with known causative genes. These genes, ''CHRNA4'', ''CHRNB2'', and ''CHRNA2'', encode various nicotinic acetylcholine receptor α and β subunits.
==Signs and symptoms==
ADNFLE is a partial epilepsy disorder characterized by brief violent seizures during sleep. Seizures are complex, consisting of arm and leg movements, fist clenching, and vocalizations such as yelling and moaning. These seizures often occur in clusters and can first manifest in childhood. Diagnosis is often initially incorrectly made as nightmares, night terrors, parasomnias and various psychiatric disorders.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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